Vitamin B6 is a group of water-soluble compounds (vitamers) that functions as a coenzyme in many reactions involved in amino acid, carbohydrates and lipid metabolism as well as the production of antibodies and red blood cells.* Pyridoxal 5'-phosphate (P-5’-P) is the metabolically active form of vitamin B6, and it is involved in over 100 enzymatic reactions, many of which are related to protein metabolism. In addition to protein metabolism, vitamin B6 helps release glycogen from the liver and muscles, suggesting its utility in exercise performance. The versatile vitamin/coenzyme also has been shown to protect lipids and proteins against glycation reactions as well as aid homocysteine methylation, indicating its role in supporting cardiovascular health. Pyridoxal 5'-phosphate (P-5’-P) helps maintain the balance of sodium and potassium, which regulates body fluids and promotes healthy functioning of the nervous and musculoskeletal systems. To top it off, vitamin B6 also affects cognitive function and mood, and it is required for the biosynthesis of critical neurotransmitters, including GABA, dopamine, noradrenaline, serotonin.